Contribution of Receptors, Transcription Factors, and Genes in the Induction of Neuroinflammation

Feb 4, 2017 by in NEUROLOGY Comments Off on Contribution of Receptors, Transcription Factors, and Genes in the Induction of Neuroinflammation

Fig. 4.1 Cytokines and chemokines associated with neuroinflammation In addition, stimulation of glutamate, cytokine, Toll-like, bradykinin, histamine, dopamine, purinergic, GABA, endothelin, and platelet activating factor (PAF) receptors results in stimulation…

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Contribution of Transcription Factors and Genes in the Induction of Oxidative Stress

Feb 4, 2017 by in NEUROLOGY Comments Off on Contribution of Transcription Factors and Genes in the Induction of Oxidative Stress

Fig. 9.1 Oxidative stress-mediated modulation of transcription factors leads to gene transcription involved in neural cells survival and death. Glutamate (Glu), N-Methyl-D-aspartate receptor (NMDA-R), Phosphatidylcholine (PtdCho), cytosolic phospholipase A2 (cPLA2),…

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Contribution of Dietary Carbohydrates in Induction of Oxidative Stress

Feb 4, 2017 by in NEUROLOGY Comments Off on Contribution of Dietary Carbohydrates in Induction of Oxidative Stress

Fig. 8.1 Hyperglycemia-mediated formation of superoxide in the mitochondrial electron chain. Manganese-dependent superoxide dismutase (MnSOD); copper/zinc-dependent superoxide dismutase (CuZnSOD); hydrogen peroxide (H2O2); and superoxide (O2 −) Thus, hyperglycemia-mediated generation of…

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The First Descriptions of Clinical Signs

Jan 29, 2017 by in NEUROLOGY Comments Off on The First Descriptions of Clinical Signs

(1) Division of Critical Care Neurology, Mayo Clinic, Rochester, Minnesota, USA   Abstract This chapter includes 18 clinical signs seen in acute neurologic conditions. The origin of the clinical sign…

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First Descriptions of Clinical Syndromes

Jan 29, 2017 by in NEUROLOGY Comments Off on First Descriptions of Clinical Syndromes

(1) Division of Critical Care Neurology, Mayo Clinic, Rochester, Minnesota, USA   Abstract This chapter includes 15 clinical syndromes seen in acute neurologic conditions. The origin of the eponyms is…

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First Clinical Studies and Trials

Jan 29, 2017 by in NEUROLOGY Comments Off on First Clinical Studies and Trials

(1) Division of Critical Care Neurology, Mayo Clinic, Rochester, Minnesota, USA   Abstract This chapter introduces 12 landmark trials that define the field. These clinical trials involve the first testing…

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